Tretinoin - Topical Cream

Description

Tretinoin: Retinoids, such as vitamin A and retinoic acid (RA) or tretinoin, were first used in combination with Hydroquinone to enhance the penetration of Hydroquinone (Klingman and Willis, 1975). The ability of tretinoin to depigment is based on its ability to disperse keratinocyte pigment granules, interfere with pigment transfer, and accelerate epidermal turnover and, therefore, pigment loss.